Wednesday, November 6, 2019

Sum of Squares Formula Shortcut

Sum of Squares Formula Shortcut The calculation of a sample variance or standard deviation is typically stated as a fraction. The numerator of this fraction involves a sum of squared deviations from the mean. In statistics, the formula for this total sum of squares is ÃŽ £ (xi - xÌ„)2 Here the symbol xÌ„ refers to the sample mean, and the symbol ÃŽ £ tells us to add up the squared differences (xi - xÌ„) for all i. While this formula works for calculations, there is an equivalent, shortcut formula that does not require us to first calculate the sample mean. This shortcut formula for the sum of squares is ÃŽ £(xi2)-(ÃŽ £ xi)2/n Here the variable n refers to the number of data points in our sample. Standard Formula Example To see how this shortcut formula works, we will consider an example that is calculated using both formulas. Suppose our sample is 2, 4, 6, 8. The sample mean is (2 4 6 8)/4 20/4 5. Now we calculate the difference of each data point with the mean 5. 2 – 5 -34 – 5 -16 – 5 18 – 5 3 We now square each of these numbers and add them together. (-3)2 (-1)2 12 32 9 1 1 9 20. Shortcut Formula Example Now we will use the same set of data: 2, 4, 6, 8, with the shortcut formula to determine the sum of squares. We first square each data point and add them together: 22 42 62 82 4 16 36 64 120. The next step is to add together all of the data and square this sum: (2 4 6 8)2 400. We divide this by the number of data points to obtain 400/4 100. We now subtract this number from 120. This gives us that the sum of the squared deviations is 20. This was exactly the number that we have already found from the other formula. How Does This Work? Many people will just accept the formula at face value and do not have any idea why this formula works. By using a little bit of algebra, we can see why this shortcut formula is equivalent to the standard, traditional way of calculating the sum of squared deviations. Although there may be hundreds, if not thousands of values in a real-world data set, we will assume that there are only three data values: x1 , x2, x3. What we see here could be expanded to a data set that has thousands of points. We begin by noting that( x1 x2 x3) 3 xÌ„. The expression ÃŽ £(xi - xÌ„)2 (x1 - xÌ„)2 (x2 - xÌ„)2 (x3 - xÌ„)2. We now use the fact from basic algebra that (a b)2 a2 2ab b2. This means that (x1 - xÌ„)2 x12 -2x1 xÌ„ xÌ„2. We do this for the other two terms of our summation, and we have: x12 -2x1 xÌ„ xÌ„2 x22 -2x2 xÌ„ xÌ„2 x32 -2x3 xÌ„ xÌ„2. We rearrange this and have: x12 x22 x32 3xÌ„2 - 2xÌ„(x1 x2 x3) . By rewriting (x1 x2 x3) 3xÌ„ the above becomes: x12 x22 x32 - 3xÌ„2. Now since 3xÌ„2 (x1 x2 x3)2/3, our formula becomes: x12 x22 x32 - (x1 x2 x3)2/3 And this is a special case of the general formula that was mentioned above: ÃŽ £(xi2)-(ÃŽ £ xi)2/n Is It Really a Shortcut? It may not seem like this formula is truly a shortcut. After all, in the example above it seems that there are just as many calculations. Part of this has to do with the fact that we only looked at a sample size that was small. As we increase the size of our sample, we see that the shortcut formula reduces the number of calculations by about half. We do not need to subtract the mean from each data point and then square the result. This cuts down considerably on the total number of operations.

Sunday, November 3, 2019

Climate, geography, income per capita and growth Literature review

Climate, geography, income per capita and growth - Literature review Example Geography and environment has a closer impact on socio-economic development of a region. Historical data has revealed that geography has some effect on shaping the economic history. However, the amount of variance is an important consideration. Tropics are varied by braod climatic zones and economies as well (Torres & Mendez, 2000; 2002, Inter-American Development Bank, 2000). As a result, the research would identify the key geographical and climatic factors from the national database and analyze its relationship with income per person longitudinal data for a time period of 1950 to 2014. This paper will analyze this variance to test and interpret the condition of multicollinearity using a regression analysis, as some geographical factors might be highly correlated impacting the ultimate results. Analyzing the relationship between the major geographical features, such as altitude, climate, topography on the economic growth and prosperity with individual municipal incomes and their inequalities. Previous research has established a close relationship between economic development and geographical characteristics, such as topography, altitude, precipitation, temperature and rainfall etc., of a region. In this pretext, the tropical economies have lower income levels and growth rates than rest of the world. Temperate regions are more prosperous in this respect. The impact of geography on economic performance was considered exogenous for a very long time by economists (Rodrik & Trebbi, 2004). In fact there are direct channels influencing the effect of geography on productivity (Fujita, Krugman & Venables, 1999; Gallup, Sachs & Mellinger, 1999), in terms of productivity of primary activities, such as agriculture, farming, mining, fishing and forestry (Safford & Palacios, 2002). The classical Malthusian theory has stressed on how extremes of climate and temperature might diminish the productivity of labor as a consequence of spillovers and positive

Friday, November 1, 2019

Mutually Assured Destruction Research Paper Example | Topics and Well Written Essays - 3000 words

Mutually Assured Destruction - Research Paper Example Their own children fought the first man versus man battle with Abel as the first human casualty. From then onwards, from the Book of Genesis to the Book of Revelation, every chapter exposes the wars human beings have had to win. On the other hand, the theory of evolution paints an even more difficult birth for the human kind. It is survival of the fittest. Perhaps the Homo sapiens specie is indeed the fittest because it had survived the tests of time and nature. Sadly though, we did survive millions of years of evolution only to stand at the brink of total annihilation on our own hands. Apparently, Armageddon would come not through the Beast of the Book of Revelation or through a colliding giant asteroid. Contrary to the prophecies of prophets and filmmakers, the end of days would be brought by the beast of man called nuclear weapon when the interests of the world’s powers collide. Worse, there is no need for a world war three in order for the world to be in chaos. All it need s is a war between two nuclear superpowers and the earth will stand still, or whatever is left of it. War in this day and age is unthinkable but we need to think about it. War in the twenty first century is simply mad. Well, as a matter of fact, it is MAD. This paper shall look into the theory of war called Mutually Assured Destruction (MAD) and its role in the World War I, World War II and the Cold War. Moreover, this paper shall explore into the future of weapons and war in light of the technological advancements of our time. The MAD Theory When John F. Kennedy took over the reins on January 20, 1961, he declared in his inaugural address: "Let every nation know, whether it wishes us well or ill, that we will pay any price, bear any burden, meet any hardship, support any friend, oppose any foe, to assure the survival and the success of liberty.† Essentially, this was a confirmation that from then onwards, the USSR will never catch up on the mighty USA. The government will do everything in its power and utilize all available resources to ensure that the USA shall remain the world’s guardian of democracy and anyone who chose to disagree and oppose shall feel its power. True to his words, the President brought in Robert McNamara from the business sector to help him pound the competition and ensure its monopoly on world power. And McNamara managed the Department of Defense like he would a multinational company – always with a sharp eye on profit and always calculating the odds with the aid of cost-benefit analysis. The US developed more products that would be a big hit in the world market (read: weapons that would destroy the world). And the business of war was indeed good. President John F. Kennedy’s Secretary of Defense Robert McNamara introduced the world to the concept of Mutually Assured Destruction otherwise known as simply MAD. In his own words: â€Å"Mutual Assured Destruction is the foundation of deterrence†¦ If you want a stable nuclear world†¦ it requires that each side be confident that it can deter the other. And that requires that there be a balance and the balance is the understanding that if either side initiates the use of nuclear weapons, the other side will respond with sufficient power to inflict unacceptable damage. Mutual Assured Destruction. So Mutual Assured Destruction is the foundation of stable deterrence in a nuclear world. It's not mad, it's logical.† (Interview) Robert McNamara is credited with the doctrine of Mutually Assur

Wednesday, October 30, 2019

Video case report Essay Example | Topics and Well Written Essays - 1000 words

Video case report - Essay Example However on this day, to everyone’s amazement, calls, emails and letters started flooding in, with every customer expressing dissatisfaction on various areas such as: product dissatisfactions, service delivery, the speed of the response and attention offered to the customers towards their complaints. The results were drastically affecting every sector within the firm, such as reduction on the sales, disruption on our production and dismissal of various workers. To provide a permanent solution, the firm had to put various factors in to account by laying out strategic measures to curb that occurrence ever repeating itself again. According to (Meredith 2010), a customer makes the business run and there is no particular firm that can chase away customers willingly; but the simple mistakes that various firms normally make, may be acts that result in chasing away customers in disguise. In every firm as many business people always put it, the â€Å"customer is the king† but may be this is what our firm didn’t establish or didn’t have established. ... According to (Zairi 2000), â€Å"Customers are the main purpose for running a firm, plus rather than them depending on the firm, the firm depends on them†. This indicates the importance of a gentle attachment between the firm and the customers. For (Hansemark and Albinsson 2004), they defined satisfaction as â€Å"overall customer attitude towards a service provider or the emotional reaction on what customers anticipate in relation to what they receive on their desired needs†. According to (Anderson 2000), customer loyalty is actually the result of an organization creating an atmosphere conducive to customers becoming repeat shoppers so that they can maintain or increase sales. Customer loyalty can only be achieved by providing and delivering what the customers desire and expect. Also (Oliver 1997), termed customer loyalty as that deep commitment to re-purchase a certain preferred product or service consistently in the future despite changes or influences with possibili ty of causing a change in the marketing behavior. Hokanson {1995), explains various factors that affect the level of customer satisfaction. This includes: employees’ knowledge on the product, friendliness, courteous and helpful staff, competitive pricing, good value of the product, billing clarity, timeliness and accuracy and quick service delivery. The most affected area as depicted in our firm by the dissatisfaction of the customers was on the profitability. According to (Hoyer 2001), satisfied customers provide the foundation of every successful business organization as it leads to repeat purchases and loyalty on the brands supplemented by a positive word of mouth. According to various researchers’, dissatisfaction of customers leads to

Monday, October 28, 2019

Socrates Stand on Democracy Essay Example for Free

Socrates Stand on Democracy Essay Having emphasized upon me the advantages of democracy, I have always believed that it is the best system to implement in a country. Ignoring the flaws and weaknesses of this type of system, I thought that the benefits outweigh all costs. I assume that giving the power to the people is better than having one person rule the state. However, in Plato’s account on the life of his mentor Socrates, we are able to see both sides of the spectrum: the pros and cons of democracy which are accounted in Plato’s dialogues, the Apology and the Crito. Socrates, having been accused of impiety, is brought to trial in front of the jury of Athens. In his defense, he points out the flaws of a democratic system, but he has an underlying intention to improve it. Thus, despite his criticisms on the use of rhetoric, involvement in politics, and the opinions of the majority, Socrates generally takes a pro-democracy approach on his purpose of being in Athens, the importance of examining truth and life, and the significance of respecting the law. Socrates is known in Athens for his dialectic approach of questioning and examining the ideas of the people. He has unintentionally annoyed many Athenian citizens which has made him infamous. This has led other people, such as Meletus, to press charges against him. In his defense, Socrates sets himself apart from others who bring their family and friends as a kind of an appeal to the jurymen. Through tears and emotional plea, they beg to be acquitted. However, Socrates does not intend to present such acts as he places greater significance to his, the jury’s, and the city’s reputations. He considers it shameful to try to win approval through emotional appeal rather than the truth as it brings dishonor to the city (37). Socrates points out then that it is the role of a juryman not to acquit someone who seems favorable, but â€Å"to judge according to Reusi 2 law†¦ [which] he has sworn to do† (37). It is the jury’s responsibility to give verdict based on truth and logic. Through the oath that they have taken, the jurymen have pledged to accept this duty; therefore, to favor someone is against the law. Socrates criticizes how the public has taken advantage of the use of rhetoric to win arguments in any way possible; such as appealing to emotions which has dominated and influenced the community and its decisions. These statements highlight the nti-democratic notion of Socrates; he reproaches the majority of the citizens who have based their judgments on faulty premises. Moreover, he connotes that it is more important to listen to the persuasive arguments of â€Å"the one† that uses truth and logic, rather than the pathetic acts of â€Å"the many†. However, beneath the criticisms, Socrates tries to enlighten the members of the jury, who have a stake at public decisions, of their purposes as jurymen of the state. He reminds them of their sworn duties, and encourages them not to give in to emotional appeal, as this per se is an attack to democracy and to the law that makes the city. Additionally, Socrates explains to the jury why despite his continuous efforts to meddle on personal matters, he has never pursued on occupying political positions. This, he says, is due to the â€Å"spiritual† (34) voice that speaks to him only when he is about to do something he is not supposed to do. He believes that if he had taken part in politics, he would not have survived through the years, because he would debate against the authority or the public, and stop the unlawful actions in the state (34). Socrates upholds that â€Å"a man who really fights for justice must lead a private, not a public, life if he is to survive for even a short time† (34). He points out that in order to live a just and peaceful life, it is better for a man to stay away from â€Å"public† activities where unlawful events usually take place. It is more important to live a â€Å"private† life, â€Å"fight[ing] for justice† at its core by dealing in â€Å"private affairs† (34). Reusi 3 Socrates is considered as taking an anti-democratic stand when he has chosen not to get involved with the government, considering that the government is the people. Yet, he implies that the people would not favor anyone that opposes injustice which seems to be the common dealings in politics. He believes that he would â€Å"have died long ago† (34), although this is not his ultimate concern. What he truly cares about is â€Å"not to do anything unjust or impious† (32). Despite his criticisms on politics, Socrates is essentially reminding the people, especially those in authority, to serve a just and virtuous life. Outwardly stating the current situation of the government, he aims to provide the people a portrait of the shallow kind of democracy that they have come to maintain. Socrates seeks to prompt the majority to uphold the true sense of democracy, of fighting for justice and living life accordingly. Furthermore, Socrates uses his dialectical approach with his friend Crito in examining the contrast between the knowledge of â€Å"the one† and the pseudo-knowledge of â€Å"the many†. He uses an analogy of a man involved in physical activities, whom must listen to the advice of the true expert in his training, rather than the opinions thrown by other people who barely know anything about these activities. Anyone who places a higher regard to the thoughts of the majority, rather than to the knowledge of the one who possess it, puts himself on greater â€Å"harm† (47). Socrates adds that if we disobey the one who seeks to improve us, â€Å"we shall harm and corrupt that part of ourselves that is improved by just actions and destroyed by unjust actions† (48). This is antidemocratic in a way that it explicitly denotes the greater relevance of â€Å"the one† as opposed to the false opinions of â€Å"the many†. Democracy is based upon the judgment of the majority; however, if they collectively agree on faulty decisions, it brings destruction to the state and corruption to its citizens. As Socrates puts it, â€Å"we should not then think so much of what the majority will say about us, but what he will say who understands justice and injustice, the one, that is, and the truth Reusi 4 itself† (48). Despite his arguments, he suggests that the majority learns to listen to the one who possess true wisdom, so as to strengthen the grounds of democracy. The united opinions of the many can be given greater significance when it is based on the wisdom of the one who seeks â€Å"to improve† the city. In spite of the anti-democracy view of Socrates regarding rhetoric, politics, and the majority, he presents a pro-democratic stand on his true purpose of being in Athens. He addresses the jury that it would be a mistake to condemn him since he has been brought to the city of Athens according to the god’s will. He compares himself to a â€Å"gadfly† that tries to wake the â€Å"great and noble horse† that has become inactive and lazy (33). This, Socrates believes, is his purpose for being placed in the city by the god. He â€Å"never [ceases] to rouse each and every one† of the citizens, to convince and to criticize them all the time (33). In this passage, Socrates shows how much he cares for the city as he, a â€Å"gadfly†, tries to motivate the â€Å"noble† city of Athens to reach its full potential. By this, Socrates expresses a pro-democratic attitude as he believes that by his consistent approach to its citizens, he hopes to keep the city active, knowing that it has many capabilities that have not been fully developed. Moreover, Socrates states that he will continue to follow the god rather than the demands of the public for him to cease his quest of constant dialectic. He adds that with every Athenian he meets, Socrates would cross-examine him. He would denote that by being a citizen of the â€Å"noblest† city with high regards for both â€Å"wisdom and power†, it is a shameful thing to put such high importance on material possessions and status while disregarding â€Å"wisdom or truth, or the best possible state of [the] soul† (32). He would reprimand those who were proven to value superficial things instead of the more important ones. Socrates maintains that â€Å"the unexamined life is not worth living for men† (39). He motivates the citizens to examine the truth and virtue Reusi 5 as he affirms that â€Å"the most important thing is not life, but the good life† (48). This is very prodemocratic in a sense that the city aims to accomplish this highest form of living, which can be achieved only if each citizen is able to reflect upon himself, and realize his own way of living. He stresses the importance of not indulging oneself with material desires, but focusing only on the â€Å"best possible state of [the] soul† (32). Once every citizen is able to live a life worthy of the â€Å"noble† city of Athens can the city fully establish a strong democracy that highlights â€Å"wisdom†, justice, and â€Å"truth† (32). Lastly, in Crito’s attempt to persuade Socrates to escape the city and his death, Socrates has emphasized the significance of respecting the law. He imagines being faced by the law, ordering him that he must either convince his city according to what is just, or submit himself in any given circumstance in accord to the position assigned to him by his country (51). Therefore, it is wicked to bring harm to one’s own country even â€Å"after being wronged not by†¦ the law, but by men† (54). Socrates is sentenced to death because of the decision of the majority, but not of the law. He uses the law to represent the entire city, for the law makes and embodies the ideals of the state. His notion is pro-democratic as he expresses his respect for the decrees that ultimately establishes the democratic system of Athens. Despite being persecuted by men, he still considers the law as just and equitable. When we divert from the true purpose of a system, the costs are as significant as the benefits. Plato’s account of Socrates enables us to have a two-way view on democracy in considering both its advantages and disadvantages. Underlying his criticisms to certain aspects of this system is Socrates’ greater pursuit to improve and develop the state.

Saturday, October 26, 2019

Daniel Clowes Ghost World: Argumentative Comparison Essay -- Ghost Wo

Pictured on the back cover of the comic book "Ghost World," by Daniel Clowes, are the two main characters of the book in full color. This strikingly significant image, surely shrugged off by most Clowes' readers, represents worlds of diversity within the frames of the book. Sporting pink spandex pants underneath her goldfinch yellow skirt and a blue t-shirt to match perfectly, Enid seems to live her life outside the bubble. She's a very dynamic girl, especially interested in her surroundings and people around her. On the other hand, Becky is dressed like a "typical" girl, with a long black skirt and a white blouse, thus representing her conforming presence in the world. Becky is much more passive than Enid, going with the flow of things just living life. The contrasting personalities of Enid and Becky come ironically, being best friends. However, it brings out their defining qualities in the comic book while quietly calling attention to the values of life, what is real an d what is not. The title page on the second page of the book can be analyzed to show how Enid lives a different life than those on the "inside." The illustration is colored in a light hue of blue, somewhat casting a bleak and lifeless feeling. The picture shows Enid walking down the street with her hands in her pockets, back turned. Nighttime falls as the luminous moon watches down on Ghost World at dusk, casting Enid's shadow down on the sidewalk behind her. To her right is a house with window and the phrase Ghost World scrawled on the side of building. Everything in the scene is shaded and colored in a robin's egg b... ...ple, or the adorable old man who bought the pathetic flowers from the grocery store to take home to his wife. Becky doesn't notice these minute details that Enid does, nor does she care very much. In any case, they are in different worlds. Whose world is real? There's no answer to that. If it's real to them, then that's what it will be. The characters are diverse in the comic book, and it helps for the reader to not only understand the plot and distinguish between the two characters, but to show that people are naturally different, immature or mature, conforming or nonconforming. Diversity makes the world what it is, and that's as real is it can get. Work Cited Clowes, Daniel. "Ghost World" Fantagraphics (April 1, 2001)

Thursday, October 24, 2019

DNA Profiling and Ethics

DNA Profiling and Ethics Reflection Journal Vanshika Khemka 14th October 2012 â€Å"33 autorad off† On 10th September 1984, geneticist Alec Jeffrey’s wrote these three words in his red desk diary. This marked the completion of an experiment, which studied how inherited illnesses pass through families. The experiment failed entirely. (McKie, 2009) However, this led to the most profound discovery: the world’s first DNA fingerprint. Now, the smallest swab of blood or sweat can determine the identity of an individual.We will discuss this process of DNA profiling in this journal. After going into the in-depth analysis of DNA profiling, we will discuss its uses and the ethical and legal issues that swarm the subject. |What is DNA Profiling? | Formally, DNA profiling is the analysis of short, highly specific, tandem-repeated- or hypervariable- genomic sequences, minisatellites known as variable number of tandem repeats (VNTRs), to detect the degree of relatedness to ano ther sequence of oligonucleotides. Segan, 1992) It is a technique employed by  forensic scientists  to assist in the identification of individuals by their respective  DNA  profiles, which are encrypted sets of numbers that reflect a person's DNA makeup and can also be used as the person's identifier. |The Process | Deoxyribonucleic Acid (â€Å"DNA†) is a six-foot long molecule found in the nucleus of every cell in the body. With the exception of identical twins, each individual’s DNA is unique.Thus the first step in the profiling process is to obtain a sample of the individual’s DNA, which is usually done using a buccal swab (i. e. from the cheek). We could also use a sample of blood, semen or hair. This sample is then analyzed using different techniques; discussed below. |Techniques of DNA Profiling | |Restriction Fragment Length Polymorphism (RFLP) |It is a technique that exploits variations in homologous DNA sequences. It refers to a difference bet ween samples of homologous DNA molecules that come from differing locations of restriction enzyme sites, and to a related laboratory technique by which these segments can be illustrated. In this process, the DNA is first chemically extracted from the sample. It is then fragmented using restriction enzymes. These enzymes act like scissors and cut the DNA where a specific sequence occurs.By gel electrophoresis, the DNA fragments are placed in a gel through which an electric current is passed. Owing to the negative charge of the DNA, the fragments migrate toward the positively charged pole of the gel. The DNA is then denatured and Southern blotting transfers the DNA fragments to a nylon membrane. A buffer solution is pulled through the gel and membrane and absorbed in paper towels. Hybridization, brought about by radioactive probe, shows only those fragments of interest from the polymorphic area of the DNA.Autoradiography is carried out next where the blot is placed in contact with a p iece of x-ray film, where the radioactivity probe exposes the film and bands appear on the film where the probe has bound to the DNA. The results are then interpreted and in the case of a criminal investigation or civil case, it is matched against the suspect’s DNA profile, thus completing the process. (Hoeffel, 1990) This method is however very long-winded, cumbersome and the combination of all the above-mentioned steps could take about a month to complete.A large sample is required which makes it tougher. Hence other methods are adopted in recent times. |Polymerase Chain Reaction | With the invention of the polymerase chain reaction (PCR) technique, DNA profiling took huge strides forward in both discriminating power and the ability to recover information from very small (or degraded) starting samples. PCR greatly amplifies the amounts of a specific region of DNA.This process increases the number of copies of the allele, making enough DNA to allow the test to be performed on what may have originally been a DNA sample of insufficient molecular weight. Due to this technique the test can be conducted using a single hair strand. (Hoeffel, 1990) This process consists of a series of 20-40 repeated temperature changes, called cycles, with each cycle commonly consisting of 2-3 discrete temperature steps. The cycling is often preceded by a single temperature step (called  hold) at a high temperature (>90 °C), and followed by one hold at the end for final product extension or brief storage.The temperatures used and the length of time they are applied in each cycle depend on a variety of parameters. These include the enzyme used for DNA synthesis, the concentration of divalent ions and dNTPs in the reaction, and the melting temperature (Tm) of the primers. The rest of the process is similar to the RFLP method. The major breakthrough is the fact that now the smallest trace of evidence can be used for DNA profiling as opposed to the large samples needed in th e RFLP method. |Short Tandem Repeat Analysis |Also known as Microsatellites, short tandem repeats is used as an extension of the PCR Method. This method uses highly polymorphic regions that have short repeated sequences of DNA (the most common is 4 bases repeated, but there are other lengths in use, including 3 and 5 bases). (Hoeffel, 1990) Because unrelated people almost certainly have different numbers of repeat units, STRs can be used to discriminate between unrelated individuals. These STR  loci  (locations on a chromosome) are targeted with sequence-specific primers and amplified using  PCR.The DNA fragments that result are then separated and detected using  electrophoresis. |Amplified Fragment Length Polymorphism | This is another technique that is much faster than RFLP and uses PCR. It not only has higher reproducibility, resolution, and sensitivity at the whole genome level compared to other techniques, but it also has the capability to amplify between 50 and 100 fra gments at one time. In addition, no prior sequence information is needed for amplification (Meudt & Clarke 2007).As a result, AFLP has become extremely beneficial in the study of bacteria, fungi, and plants, where much is still unknown about the genomic makeup of various organisms. |Applications of DNA Profiling | DNA profiling is extensively used for paternity testing and forensic analysis for criminal investigations. Parental testing is the use of genetic fingerprinting to determine whether two individuals have a biological parent–child relationship.Comparing the DNA sequence of an individual to that of another individual can show whether one of them was derived from the other. Specific sequences are usually looked at to see whether they were copied verbatim from one of the individual's genome to the other. (Berry, 1991) As for forensic analysis, laboratories compare the molecular weights of fragments of DNA from the suspect sample and crime sample and decide whether the t wo fragments could have come from the same individual. There are major benefits from this technology: the potential to make speedy and robust suspected offender identi? ations through automated profile comparisons in centralized criminal justice databases; the ability to con? dently eliminate innocent suspects from investigations; the increased likelihood of generating reliable and persuasive evidence for use in court; a reduction in the cost of many investigations; the likely deterrent effect of DNA databasing on potential criminal offenders; and a possible increase in public con? dence in policing and in the wider judicial process. (Berry, 1991) We will explore the ramifications of this extensive use in the next section. Is it ethical? | Now that we know the widespread use of DNA profiling, we see the power that it has and the influence it can have when it comes to people’s lives and the verdict issued in criminal cases. But is this power justified on an ethical front? Is i t ethical to give so much power into the hands of the people responsible for carrying out these tests? Indeed, the development and application of DNA pro? ling has been widely described as the â€Å"greatest breakthrough in forensic science since ? ngerprinting. † However, the spread of forensic DNA pro? ing and databasing has also prompted a wide range of concerns about problems that may arise from the storage of tissue samples (especially those taken from individuals without consent) and the proliferating uses of genetic information by the police. (Williams & Johnson, 2006) One could say that DNA profiling violates basic ethical values. Based on the values of liberty, our rights are technically reduced by police powers, which have the right to take and retain fingerprints and DNA profiles and samples without consent. The Forensic Use of Bioinformation: Ethical Issues, 2007) â€Å"So act that you use humanity, whether in your own person or in the person of any other, always at the same time as an end, never merely as a means†; these words of wisdom imparted by Kant, also suggest that DNA profiling and the freedom to use that as evidence without explicit permission of the individual concerned would be using them as a means to an end and not an end in themselves. Therefore it can be argued that using DNA profiling takes away autonomy. The Forensic Use of Bioinformation: Ethical Issues, 2007) Spatial privacy is â€Å"a state of non-access to the individual’s physical or psychological self†. This is invaded by the nonconsensual taking of biological samples and fingerprints, and, to a lesser extent, by unwanted surveillance of the individual. And as can be inferred by the very nature of DNA profiling, informational privacy and anonymity is infringed upon by using samples obtained from databases and tests. (The Forensic Use of Bioinformation: Ethical Issues, 2007)Additional issues arise if identifiable samples or profiles on a forensic d atabase are used for research outside the narrow context of identification and police investigations. Using DNA profiling for paternity testing and for determining one’s lineage can be very harmful as it violates the privacy of the people concerned. It could cause potential moral and mental harm to the parents and the children concerned as entire families can be uprooted as a result of this. Past criminal cases which used paternity testing also prove that relatives and families can be affected mentally as well as physically.People in witness protection programs as well as people on the police databases can be negatively affected if a previously unknown family link is reestablished without their knowledge and consent. (Haimes, 2006) The list of legal and ethical concerns is endless. The question the arises that which side wins? Benefits of DNA profiling, or the issues concerning DNA profiling? |Which side is stronger? | Having seen the costs and benefits of DNA profiling and i ts usage, the benefits are debatable on moral and ethical grounds.However, in my personal opinion, it does not have to be black and white; good or bad. There can be a grey area, a middle ground, where DNA profiling is neither entirely correct nor entirely wrong. There have been cases where DNA evidence has saved many innocent lives and incriminated people who had been causing immense harm to others. Thus, we should pass legislations, which aim at curbing violations and encouraging true and just practices. In the cases where the DNA of individuals is being used as evidence or if parental testing is being done, their should be informed consent by the individuals.They should be aware of the sensitive nature of the information and should be expressly asked for consent to have the data published or used as evidence. The National DNA Database set up in the UK is an example of the dangers and benefits DNA profiling can hold. Personally, a national DNA database in all countries would be a v ery risky venture as a lot of personal information would be at stake and inter country rivalries could result. We have established the power of DNA profiling and the power that people who have access to this information have. So I would like to end with a quote.One’s interpretation of this quote can determine where they stand on the matter. â€Å"It is time for you to gather some idea of what power means. The first thing you must realize is that power is collective. The individual has power in so far as he ceases to be an individual†¦ The second thing for you to realize is that power is power over human beings. Over the body- but, above all, over the mind. Power over matter- external reality, as you would call it- is not important. Already our control over matter is absolute. † – George Orwell, Nineteen Eighty-Four Bibliography | Berry, D. A. (1991). Inferences Using DNA Profiling in Forensic Identification and Paternity Cases. Statistical Science , 6 (2), pp. 175-205. Haimes, E. (2006, June 1). Social and Ethical Issues in the Use of Familial Searching in Forensic Investigations: Insight from Family and Kinship Studies. Journal of Law, Medicine and Ethics , 263-276. Hoeffel, J. C. (1990, January). The Dar Side of DNA Profiling: Unreliable Scientific Evidence Meets the Criminal Defendant. Stanford Law Review , 42 (2), pp. 465-538.McKie, R. (2009, May 24). Eureka moment that led to the discovery of DNA fingerprinting. Retrieved October 10, 2012, from The Guardian: http://www. guardian. co. uk/science/2009/may/24/dna-fingerprinting-alec-jeffreys Segan, C. J. (1992, February 15). DNA Profiling. The Dictionary of Modern Medicine . The Forensic Use of Bioinformation: Ethical Issues. (2007, September). NuField Council on Bioethics . Williams, R. , & Johnson, P. (2006, June 1). Inclusiveness, Effectiveness and Intrusiveness: Issues in the Developing Uses of DNA Pro? ling in Support of Criminal Investigations. Journal of Law, Medicine and Et hics , 234-247. Wikipedia